Neuromodulators

Neuromodulators—often called wrinkle relaxers—are injectable medications that soften lines and wrinkles caused by repeated facial expressions like frowning, squinting, raising your brows, or smiling.
kaboompics botox fillers facial treatments skincare in aesthetic medicine clinic

What Are Neuromodulators aka Wrinkle Relaxers?

Neuromodulators—often called wrinkle relaxers—are injectable medications that soften lines and wrinkles caused by repeated facial expressions like frowning, squinting, raising your brows, or smiling.
They’re made from a purified form of botulinum toxin type A that communicates with the tiny muscles just beneath the skin, helping them relax in a controlled, precise way.
At Lueur Aesthetics, we work with a curated selection of neuromodulators to tailor treatment to your unique anatomy and goals, including:
Each brand has its own personality in terms of onset, spread, and longevity, but they all share the same purpose: to soften unwanted lines and enhance your natural expression so you look refreshed—not frozen.

What Neuromodulators Treat

Common Face & Eye Areas

Forehead lines – horizontal lines from raising your brows

Frown lines ("11s") – vertical lines between the eyebrows from squinting or concentrating

Crow's feet – fine lines at the outer corners of the eyes

Bunny lines – crinkling lines along the bridge of the nose when you smile or laugh

Chin dimpling – "orange peel" or pebbled texture in the chin

Downturned mouth corners – softening the muscles that pull the corners of the mouth downward

Brow lift – subtly lifting and opening the eye area by balancing specific muscles

Lip flip – relaxing the muscle around the mouth so the upper lip gently rolls outward, appearing fuller without filler

Gummy smile – reducing how much gum shows when you smile

Vector 2026 04 15T060045.655
Common Face & Eye Areas
Jawline & Neck: The Nefertiti Neck Lift
Vector 2026 04 15T060045.655
Jawline & Neck: The Nefertiti Neck Lift

We can also use neuromodulators to contour and refine the lower face and neck with what’s known as the Nefertiti Neck Lift. This approach targets the platysmal bands and muscles along the jawline to:

Soften vertical neck bands

Help reduce a 'pulled down' or heavy look in the lower face

Create a more defined jawline and smoother neck profile

This is a beautiful option for patients who are noticing early jowling or neck banding but aren’t ready for surgical intervention.

Nose Slimming & Tip Lift​

With careful, anatomically precise injections, neuromodulators can also contribute to subtle nose refinement:

Nose slimming: Strategic injections can help reduce excessive nostril flare and soften muscular tension around the sides of the nose.

Nose tip lift: By relaxing the muscle that pulls the nasal tip downward when you speak or smile, neuromodulators can help the tip appear slightly lifted.

Vector 2026 04 15T060045.655
Nose Slimming & Tip Lift​
Functional Uses
Vector 2026 04 15T060045.655
Functional Uses
Beyond aesthetics, neuromodulators are also used (often off-label) to help with:

Teeth grinding / jaw clenching (masseter injections)

Tension-related headaches or migraines

Excessive sweating (hyperhidrosis) in areas like the underarms, hands, feet, or scalp

What to Expect

Your Consultation

Every neuromodulator treatment at Lueur Aesthetics starts with a thoughtful evaluation:

From there, we’ll recommend the right product (Botox, Dysport, Xeomin, Jeuveau, Letybo, or Daxxify) and a dosing strategy tailored to your anatomy and desired outcome.

Vector 2026 04 15T060045.655
skincare
skin
Vector 2026 04 15T060045.655
During Your Treatment

Most patients feel comfortable going straight back to work or daily activities after treatment.

After Your Treatment

You’ll receive personalized aftercare instructions, which may include:

Results do not appear instantly. Typical timeline: Day 1–2: Minimal visible change. Day 3–5: You start to notice softening. Day 7–14: Full results visible. After 2 weeks: Small adjustment if needed.

Vector 2026 04 15T060045.655
cream

How Neuromodulators Work

Every facial expression starts with a message from your nerves telling your muscles to contract. Neuromodulators temporarily calm that conversation.

1

Targeted injections:
Your provider injects a tiny amount of neuromodulator into specific muscles responsible for the lines or movement you’d like to soften.

2

Signal interruption:
The neuromodulator blocks the release of acetylcholine, the chemical messenger that tells the muscle to contract.

3

Muscle relaxation:
The muscle relaxes just enough to reduce excessive movement—but not enough to erase your natural expression when properly dosed and placed.

4

Smoother skin:
As the muscle contracts less forcefully, the overlying skin folds less, allowing existing lines to soften and preventing new ones from becoming deeply etched.
840 1

Longevity

Neuromodulator FAQ's

  • Who is a good candidate?
  • What age should I start?
  • Will I look frozen or fake?
  • How soon will I see results?
  • How long do results last?
  • Do injections hurt?
  • Is there downtime?
  • What are the risks?
  • Can I combine with filler or other treatments?
  • Neuromodulators vs. filler — what's the difference?
Who is a good candidate?

Healthy adults not pregnant or breastfeeding, bothered by lines that show up when you frown, squint, raise your brows, or smile. Also great preventatively.

What age should I start?

There's no 'right' age—it's more about your anatomy, genetics, lifestyle, and goals. Some start in their mid-20s to early 30s for prevention.

Will I look frozen or fake?

You shouldn't. When dosed properly and placed thoughtfully, the goal is always: refreshed, not overdone.

How soon will I see results?

Usually start to notice changes within 3–5 days, with full results around 7–14 days.

How long do results last?

Most neuromodulators last about 3–4 months. Daxxify may last up to 6 months or more.

Do injections hurt?

Most patients find treatments very tolerable—quick pinches or tiny stings. Numbing can be used if needed.

Is there downtime?

Minimal. Most people go right back to work or social plans the same day.

What are the risks?

Common temporary side effects include redness, swelling, tenderness, or bruising. Less common: asymmetry, eyelid or brow heaviness, or unwanted spread.

Can I combine with filler or other treatments?

Yes. Neuromodulators pair beautifully with dermal fillers, PRP/Derma treatments, skin rejuvenation, and medical-grade skincare.

Neuromodulators vs. filler — what's the difference?

Neuromodulators relax muscles to soften lines from movement. Fillers add structure, shape, or volume. Many patients benefit from both.

Brand Details
Botox® Onset: 3–5 days (full at 7–14)
Duration: ~3–4 months
Feel: Focused, precise
Best for: Forehead, 11s, crow’s feet, brow lift, chin, gummy smile
Dysport® Onset: 2–3 days (full at ~7)
Duration: ~3–4 months
Feel: Slightly broader spread
Best for: Larger areas like forehead; quicker onset
Xeomin® Onset: 3–5 days (full at 7–14)
Duration: ~3–4 months
Feel: Clean, “pure” formulation
Best for: Patients wanting fewer accessory proteins
Jeuveau® Onset: 2–4 days (full at ~7–10)
Duration: ~3–4 months
Feel: Similar to Botox, smoother
Best for: Frown lines, forehead, crow’s feet; younger/preventative patients
Letybo™ Onset: 3–5 days (full at ~14)
Duration: ~3–4 months
Feel: Precise, refined
Best for: Upper face lines (11s, forehead, crow’s feet)
Daxxify® Onset: 1–3 days (full at ~7–14)
Duration: ~4–6 months
Feel: Focused, long-acting
Best for: Fewer visits; strong frown/forehead lines